Disseminated intravascular coagulation in transfusion-associated graft-versus-host disease. Report of two cases.

Investigation Giant Placental Chorioangioma Associated with Neonatal Sepsis-like Disease: A Case Report

Giant chorioangioma is a placental tumor associated with gestational complications such as preeclampsia, polyhydramnios and hemorrhage. In addition, this tumor might lead to the incidence of non-immune fetal hydrops, heart failure, anemia, thrombocytopenia, weight loss and death among neonates. In this case report, the clinical image of a term newborn (weighing 2800 g) with one-minute Apgar sco...

Treatment of chronic cutaneous graft versus host disease (GVHD) with photochemotherapy with Psoralen (PUVA): A report of five cases

Chronic graft versus host disease (GVHD) remains the most common late complication of allogenic stem cell transplantation and the most frequent cause of morbidity and mortality in these patients. To control this condition, immunosuppressive drugs are usually administered at a high dose and for a long time, which may result in several side effects. 5 patients with clinically and histopathologica...

Second bone marrow transplantation for patients with thalassemia: risks and benefits.

A recent paper by Angelucci and Baronciani discussed numerous aspects of thalassemia major with special attention to two dilemmas. The first is the choice between transplantation, which is still defined as the only curative treatment but bears chances of severe complications such as chronic extensive graft versus host disease (GVHD), and conservative treatment which will eventually lead to deat...

Secondary haemorrhagic disease of the newborn.

were born prematurely; 3 suffered birth asphyxia; and 3 became hypothermic. Laboratory studies showed fibrin degradation products, low platelet counts, and deficient coagulation factors. At necropsy extensive subarachnoid haemorrhages of a characteristic type were seen in all cases, and intravascular fibrin deposits in all but one. Haemorrhage in these babies is considered to be due to consumpt...

Disseminated Intravascular Coagulation in a Case of Brucellosis Misdiagnosed as Thrombotic Thrombocytopenia Purpura